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Phospho-APG8b (MAP1LC3B)-T29 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP3744a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP3744a-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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- Backgrounds
Phospho-APG8b (MAP1LC3B)-T29 Antibody - Product info | |
| Application | DB
|
| Primary Accession | Q9GZQ8 |
| Other Accession | A6NCE7, Q62625, Q9CQV6, O41515, NP_073729.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 14688 Da |
Phospho-APG8b (MAP1LC3B)-T29 Antibody - Additional info | |
| Gene ID 81631 | |
| Other Names MAP1LC3B; MAP1ALC3; Microtubule-associated proteins 1A/1B light chain 3B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3-like protein 2; MAP1A/MAP1B light chain 3 B; Microtubule-associated protein 1 light chain 3 beta | |
| Target/Specificity This Phospho-APG8b(MAP1LC3B)-T29 Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding T29 of human APG8b. | |
| Dilution DB~~1:100~500 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Phospho-APG8b (MAP1LC3B)-T29 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Phospho-APG8b (MAP1LC3B)-T29 Antibody - Protein Information | |
| Name MAP1LC3B | |
| Synonyms MAP1ALC3 | |
| Function Involved in formation of autophagosomal vacuoles (autophagosomes) | |
| Cellular Location Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes | |
| Tissue Location Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver | |
Phospho-APG8b (MAP1LC3B)-T29 Antibody - Related products
AP10648a: APG8a/b (MAP1LC3A/B)
AP12484a: APG8b(MAP1LC3B) Antibody (N-term T29)
AP1802a: LC3 Antibody (APG8B) (N-term)
AP1802b: LC3 Antibody (APG8B) (C-term)
AP1802d: LC3 Antibody (APG8B) (T6)
AP1802e: APG8b (MAP1LC3B)-T93/Y99 Antibody (Center)
AP1803a: LC3 Antibody (APG8A/B)
AP1806a: Cleaved LC3B Antibody
AP3530a: Phospho-LC3B-T12 Antibody
AP3713a: Phospho-APG8b (MAP1LC3B)-T6 Antibody
AP3739a: Phospho-APG8b (MAP1LC3B)-T93/Y99 Antibody
AP3744a: Phospho-APG8b (MAP1LC3B)-T29 Antibody
AP3748a: Cleaved-APG8b (MAP1LC3B) Antibody
RI13151: MAP1LC3B predesign siRNA
DC07581: Human MAP1LC3B cDNA Clone
BP10648a: Cleaved-APG8a/b (MAP1LC3A/B) Blocking Peptide
BP1802a: LC3 Antibody (APG8b) (N-term) Blocking Peptide
BP1802b: LC3 Antibody (APG8b) (C-term) Blocking Peptide
BP1802d: APG8b (MAP1LC3B) Antibody (T6) Blocking Peptide
BP1802e: APG8b (MAP1LC3B) Antibody (T93/Y99) Blocking Peptide
BP1803a: LC3 Antibody (APG8a/b) Blocking Peptide
BP1806a: Cleaved-LC3 Antibody (APG8b) Blocking Peptide
BP3530a: Phospho-LC3 (APG8b) - T12 Antibody Blocking Peptide
BP3645a: Phospho-APG8b (MAP1LC3B)-T93 Antibody Blocking Peptide
BP3713a: Phospho-APG8b (MAP1LC3B)-T6 Antibody Blocking Peptide
Phospho-APG8b (MAP1LC3B)-T29 Antibody - Application data
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Dot blot analysis of anti-Phospho-APG8b(MAP1LC3B)-T29 Antibody Phospho-specific Pab (Cat. #AP3744a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Phospho-APG8b (MAP1LC3B)-T29 Antibody - Research Areas
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BACKGROUND
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
REFERENCES
Rouschop, K.M., et al. J. Clin. Invest. 120(1):127-141(2010) Kirkin, V., et al. Mol. Cell 33(4):505-516(2009) Othman, E.Q., et al. J. Clin. Lab. Anal. 23(4):249-258(2009) Liu, Q., et al. Ai Zheng 27(1):25-29(2008) Komatsu, M., et al. Cell 131(6):1149-1163(2007)
