|Application ||DB, E|
|Calculated MW||16838 Da|
|Antigen Region||95-121 aa|
|Other Names||Calmodulin, CaM, CALM1, CALM, CAM, CAM1|
|Target/Specificity||This Acetyl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-121 amino acids from human Acetyl.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Acetyl-CALM1(K116) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CALM, CAM, CAM1|
|Function||Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.|
|Cellular Location||Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules|
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Provided below are standard protocols that you may find useful for product applications.
Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Mototani, H., et al. J. Bone Miner. Metab. 28(5):547-553(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Liu, Y.J., et al. Obesity (Silver Spring) (2010) In press :
Benaim, G., et al. Eur. J. Biochem. 269(15):3619-3631(2002)
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