|Application ||WB, E|
|Calculated MW||72996 Da|
|Other Names||Protein phosphatase Slingshot homolog 3, 126.96.36.199, 188.8.131.52, SSH-like protein 3, SSH-3L, hSSH-3L, SSH3, SSH3L|
|Target/Specificity||This Phospho-SSH3 (Ser37) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 10-43 amino acids from human SSH3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Phospho-SSH3 (Ser37) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Nucleus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).
Niwa R.,et al.Cell 108:233-246(2002).
Ohta Y.,et al.Genes Cells 8:811-824(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Matsuoka S.,et al.Science 316:1160-1166(2007).
Daub H.,et al.Mol. Cell 31:438-448(2008).
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