|Application ||WB, E|
|Calculated MW||72996 Da|
|Other Names||Protein phosphatase Slingshot homolog 3, 22.214.171.124, 126.96.36.199, SSH-like protein 3, SSH-3L, hSSH-3L, SSH3, SSH3L|
|Target/Specificity||This Phospho-SSH3 (Ser37) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 10-43 amino acids from human SSH3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Phospho-SSH3 (Ser37) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly (By similarity).
Niwa R.,et al.Cell 108:233-246(2002).
Ohta Y.,et al.Genes Cells 8:811-824(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Matsuoka S.,et al.Science 316:1160-1166(2007).
Daub H.,et al.Mol. Cell 31:438-448(2008).
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