- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||36217 Da|
|Antigen Region||242-270 aa|
|Other Names||Progestin and adipoQ receptor family member 3, Progestin and adipoQ receptor family member III, Raf kinase trapping to Golgi, RKTG, PAQR3|
|Target/Specificity||This PAQR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-270 amino acids from the C-terminal region of human PAQR3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAQR3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi.|
|Cellular Location||Golgi apparatus membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed in a range of tissues.|
Provided below are standard protocols that you may find useful for product applications.
PAQR3 is function as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi.
Jiang, Y., et al. Mol. Cell. Biol. 30(1):78-90(2010)
Garitaonandia, I., et al. J. Recept. Signal Transduct. Res. 29(1):67-73(2009)
Luo, X., et al. Biochem. J. 414(3):399-406(2008)
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