|Application ||WB, IHC-P, FC, E|
|Other Accession||Q80ZF7, Q8VCH7, Q8HZT6|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||38087 Da|
|Antigen Region||106-135 aa|
|Other Names||Retinol dehydrogenase 10, RDH10|
|Target/Specificity||This RDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human RDH10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RDH10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.|
|Cellular Location||Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
RDH10 generates all-trans retinal from all-trans retinol and may plan an important role in the photic visual cycle. All-trans retinal is isomerized to 11-cis retinal by the retinal G protein-coupled receptor (RGR; MIM 600342) when the retinal pigment epithelium (RPE) is illuminated.
Bankovic, J., et al. Lung Cancer 67(2):151-159(2010)
Takahashi, Y., et al. Biochem. J. 419(1):113-122(2009)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009)
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