|Application ||WB, E|
|Calculated MW||63062 Da|
|Antigen Region||151-180 aa|
|Other Names||Solute carrier family 13 member 5, Na(+)/citrate cotransporter, NaCT, Sodium-coupled citrate transporter, Sodium-dependent citrate transporter, SLC13A5, NACT|
|Target/Specificity||This S13A5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human S13A5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||S13A5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed most predominantly in the liver, with moderate expression detectable in the brain and testis|
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Provided below are standard protocols that you may find useful for product applications.
S13A5 is a tricarboxylate plasma transporter with a preference for citrate.
Gopal, E., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (1), G402-G408 (2007)
Pajor, A.M. Pflugers Arch. 451(5):597-605(2006)
Inoue, K., et al. Biochem. J. 374 (PT 1), 21-26 (2003)
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