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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 2
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q5BIV9 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Calculated MW | 14522 Da |
| Antigen Region | 76-105 aa |
| Gene ID | 503542 |
|---|---|
| Other Names | Shadow of prion protein, Protein shadoo, SPRN, SHO |
| Target/Specificity | This SPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the C-terminal region of human SPRN. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SPRN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPRN |
|---|---|
| Synonyms | SHO |
| Function | Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity). |
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor |
| Tissue Location | Mainly expressed in brain. In brain, it is expressed in hippocampus. |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
SPRN has PrP(C)-like neuroprotective activity. SPRN may act as a modulator for the biological actions of normal and abnormal PrP.
References
Beck, J.A., et al. J. Med. Genet. 45(12):813-817(2008)
Van den Brulle, J., et al. BioTechniques 45(3):340-343(2008)
Premzl, M., et al. Mol. Biol. Evol. 21(12):2210-2231(2004)
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$ 295.00
$ 99.00
Cat# AP4754b
Availability: In Stock
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