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SPRN Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPRN Antibody  (C-term) AP4754b
    Western blot analysis of lysate from human brain tissue lysate, using SPRN Antibody (C-term)(Cat. #AP4754b). AP4754b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • IHC-P - SPRN Antibody  (C-term) AP4754b
    SPRN Antibody (C-term) (Cat. #AP4754b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SPRN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5BIV9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 14522 Da
Antigen Region 76-105 aa
Additional Information
Gene ID 503542
Other Names Shadow of prion protein, Protein shadoo, SPRN, SHO
Target/Specificity This SPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the C-terminal region of human SPRN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPRN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SHO
Function Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Mainly expressed in brain. In brain, it is expressed in hippocampus.
Research Areas
Citations ( 0 )


SPRN has PrP(C)-like neuroprotective activity. SPRN may act as a modulator for the biological actions of normal and abnormal PrP.


Beck, J.A., et al. J. Med. Genet. 45(12):813-817(2008)
Van den Brulle, J., et al. BioTechniques 45(3):340-343(2008)
Premzl, M., et al. Mol. Biol. Evol. 21(12):2210-2231(2004)

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$ 295.00
$ 99.00
Cat# AP4754b
(40 western blots)
Availability: In Stock
Bulk Size
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