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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SEC24C Antibody (Center)   

SEC24C Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SEC24C Antibody (Center) AP4773c
    SEC24C Antibody (Center) (Cat. #AP4773c) western blot analysis in MDA-MB435,MCF-7 cell line lysates (35ug/lane).This demonstrates the SEC24C antibody detected the SEC24C protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P53992
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 118325 Da
Antigen Region 443-470 aa
Additional Information
Gene ID 9632
Other Names Protein transport protein Sec24C, SEC24-related protein C, SEC24C, KIAA0079
Target/Specificity This SEC24C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-470 amino acids from the Central region of human SEC24C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEC24C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC24C
Synonyms KIAA0079
Function Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Cellular Location Cytoplasm. Cytoplasm, perinuclear region Endoplasmic reticulum membrane. Golgi apparatus membrane
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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Background

SEC24C is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration.

References

Stagg, S.M., et al. Cell 134(3):474-484(2008)
Yamayoshi, S., et al. Cell Host Microbe 3(3):168-177(2008)
Morgan, A.R., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B (6), 762-770 (2007)

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$ 295.00
$ 99.00
Cat# AP4773c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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