|Application ||WB, IHC-P, E|
|Other Accession||P62634, P53996, O42395, Q3T0Q6|
|Predicted||Bovine, Chicken, Mouse, Rat|
|Calculated MW||19463 Da|
|Antigen Region||67-96 aa|
|Other Names||Cellular nucleic acid-binding protein, CNBP, Zinc finger protein 9, CNBP, RNF163, ZNF9|
|Target/Specificity||This ZNF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human ZNF9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.|
|Cellular Location||Cytoplasm. Endoplasmic reticulum|
|Tissue Location||Present in all tissues examined.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF9 encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2.
Lucchiari, S., et al. J. Neurol. Sci. 275 (1-2), 159-163 (2008)
Auvinen, S., et al. Arthritis Rheum. 58(11):3627-3631(2008)
Gerbasi, V.R., et al. Mol. Cell Proteomics 6(6):1049-1058(2007)
Toth, C., et al. Muscle Nerve 35(2):259-264(2007)
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