|Application ||WB, IHC-P, E|
|Calculated MW||45987 Da|
|Antigen Region||256-282 aa|
|Other Names||UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 7, BGnT-7, Beta-1, 3-Gn-T7, Beta-1, 3-N-acetylglucosaminyltransferase 7, Beta3Gn-T7, 241-, B3GNT7|
|Target/Specificity||This B3GNT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-282 amino acids from the Central region of human B3GNT7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||B3GNT7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in keratane sulfate biosynthesis. Transfers N-acetylgalactosamine on to keratan sulfate-related glycans. May play a role in preventing cells from migrating out of the original tissues and invading surrounding tissues.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
B3GNT7 is a glycosyltransferase which may play a role in elongation of the keratan sulfate carbohydrate backbone.
Kitayama, K., et al. J. Biol. Chem. 282(41):30085-30096(2007)
Seko, A., et al. FEBS Lett. 556 (1-3), 216-220 (2004)
Kataoka, K., et al. Biochem. Biophys. Res. Commun. 294(4):843-848(2002)
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