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DDO Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DDO Antibody (Center) AP4795c
    Western blot analysis of DDO Antibody (Center) (Cat. #AP4795c) in NCI-H292 cell line lysates (35ug/lane). DDO (arrow) was detected using the purified Pab.
    detail
  • WB - DDO Antibody (Center) AP4795c
    Western blot analysis of DDO Antibody (Center) (Cat. #AP4795c) in mouse brain tissue lysates (35ug/lane). DDO (arrow) was detected using the purified Pab.
    detail
  • IHC-P - DDO Antibody (Center) AP4795c
    DDO Antibody (Center) (Cat. #AP4795c) IHC analysis in formalin fixed and paraffin embedded lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DDO Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q99489
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 37535 Da
Antigen Region 102-130 aa
Additional Information
Gene ID 8528
Other Names D-aspartate oxidase, DASOX, DDO, DDO
Target/Specificity This DDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human DDO.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDDO Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DDO
Function Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate.
Cellular Location Peroxisome.
Research Areas
Citations (0)
citation

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Background

DDO is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction.

References

Jamra, R.A., et al. Psychiatr. Genet. 19 (1), 56 (2009)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Zaar, K., et al. J. Comp. Neurol. 450(3):272-282(2002)

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$ 365.00
$ 140.00
Cat# AP4795c
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