|Application ||WB, IHC-P, E|
|Calculated MW||37535 Da|
|Antigen Region||102-130 aa|
|Other Names||D-aspartate oxidase, DASOX, DDO, DDO|
|Target/Specificity||This DDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human DDO.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DDO Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate.|
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Provided below are standard protocols that you may find useful for product applications.
DDO is a peroxisomal flavoprotein that catalyzes the oxidative deamination of D-aspartate and N-methyl D-aspartate. Flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide can serve as the cofactor in this reaction.
Jamra, R.A., et al. Psychiatr. Genet. 19 (1), 56 (2009)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Zaar, K., et al. J. Comp. Neurol. 450(3):272-282(2002)
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