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GABRG3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - GABRG3 Antibody (N-term) AP4800a
    Western blot analysis of lysates from K562 cell line and human brain, testis tissue lysate(from left to right), using GABRG3 Antibody (N-term)(Cat. #AP4800a). AP4800a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
  • WB - GABRG3 Antibody (N-term) AP4800a
    Western blot analysis of GABRG3 Antibody (N-term) (Cat. #AP4800a) in mouse brain tissue lysates (35ug/lane). GABRG3 (arrow) was detected using the purified Pab.
  • IHC-P - GABRG3 Antibody (N-term) AP4800a
    GABRG3 Antibody (N-term) (Cat. #AP4800a) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GABRG3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GABRG3 Antibody (N-term) AP4800a
    GABRG3 Antibody (N-term) (Cat. #AP4800a) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99928
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54289 Da
Antigen Region 1-29 aa
Additional Information
Gene ID 2567
Other Names Gamma-aminobutyric acid receptor subunit gamma-3, GABA(A) receptor subunit gamma-3, GABRG3
Target/Specificity This GABRG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human GABRG3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGABRG3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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GABRG3 is a family of proteins involved in the GABAergic neurotransmission of the mammalian central nervous system. GABRG3 is a member of the GABA-A receptor gene family of heteromeric pentameric ligand-gated ion channels through which GABA, the major inhibitory neurotransmitter in the mammalian brain, acts. GABA-A receptors are the site of action of a number of important pharmacologic agents including barbiturates, benzodiazepines, and ethanol (summary by Whiting et al., 1999 [PubMed 10414349]). For additional general information about the GABA-A receptor gene family, see GABRA1 (MIM 137160).


Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009)
Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)
Tabakoff, B., et al. BMC Biol. 7, 70 (2009)

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$ 295.00
$ 99.00
Cat# AP4800a
(40 western blots)
Availability: In Stock
Bulk Size
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