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>   home   >   Products   >   Primary Antibodies   >   TELO2 Antibody (C-term)   

TELO2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TELO2 Antibody (C-term) AP4808b
    Western blot analysis of TELO2 Antibody (C-term) (Cat. #AP4808b) in K562 cell line lysates (35ug/lane). TELO2 (arrow) was detected using the purified Pab.
  • IHC-P - TELO2 Antibody (C-term) AP4808b
    TELO2 Antibody (C-term) (Cat. #AP4808b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TELO2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - TELO2 Antibody (C-term) AP4808b
    TELO2 Antibody (C-term) (Cat. #AP4808b) flow cytometric analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y4R8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91747 Da
Antigen Region 786-812 aa
Additional Information
Gene ID 9894
Other Names Telomere length regulation protein TEL2 homolog, Protein clk-2 homolog, hCLK2, TELO2, KIAA0683
Target/Specificity This TELO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 786-812 amino acids from the C-terminal region of human TELO2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTELO2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TELO2
Synonyms KIAA0683
Function Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Cellular Location Cytoplasm. Membrane. Nucleus. Chromosome, telomere
Citations (0)

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TELO2 is a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.


Collis, S.J., et al. Mol. Cell 32(3):313-324(2008)
Takai, H., et al. Cell 131(7):1248-1259(2007)
Collis, S.J., et al. Nat. Cell Biol. 9(4):391-401(2007)

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Cat# AP4808b
(40 western blots)
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