|Application ||WB, IHC-P, E|
|Calculated MW||53189 Da|
|Antigen Region||310-338 aa|
|Other Names||N-lysine methyltransferase SETD6, 211-, SET domain-containing protein 6, SETD6|
|Target/Specificity||This SETD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the C-terminal region of human SETD6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SETD6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein-lysine N-methyltransferase. Monomethylates 'Lys- 310' of the RELA subunit of NF-kappa-B complex, leading to down- regulate NF-kappa-B transcription factor activity (PubMed:21131967). Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal (By similarity).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004)
Suzuki, Y., et al. Genome Res. 14(9):1711-1718(2004)
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