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SETD6 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SETD6 Antibody (C-term) AP4848b
    Western blot analysis of SETD6 Antibody (C-term) (Cat. #AP4848b) in WiDr cell line lysates (35ug/lane). SETD6 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - SETD6 Antibody (C-term) AP4848b
    SETD6 Antibody (C-term) (Cat. #AP4848b) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SETD6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q8TBK2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 53189 Da
Antigen Region 310-338 aa
Additional Information
Gene ID 79918
Other Names N-lysine methyltransferase SETD6, 211-, SET domain-containing protein 6, SETD6
Target/Specificity This SETD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the C-terminal region of human SETD6.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSETD6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SETD6 {ECO:0000303|PubMed:21515635, ECO:0000312|HGNC:HGNC:26116}
Function Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulation of NF-kappa-B transcription factor activity (PubMed:21131967, PubMed:30189201, PubMed:21515635). Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal (By similarity). Methylates PAK4.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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References

Kimura, K., et al. Genome Res. 16(1):55-65(2006)
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004)
Suzuki, Y., et al. Genome Res. 14(9):1711-1718(2004)

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$ 182.50
$ 70.00
Cat# AP4848b
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