CNGA2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
---|---|
Primary Accession | Q16280 |
Other Accession | Q00195, Q28718, Q62398, Q03041 |
Reactivity | Human |
Predicted | Bovine, Mouse, Rabbit, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 76048 Da |
Antigen Region | 75-102 aa |
Gene ID | 1260 |
---|---|
Other Names | Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2, Cyclic nucleotide-gated channel alpha-2, CNG channel alpha-2, CNG-2, CNG2, CNGA2, CNCA, CNCA1, CNCG2 |
Target/Specificity | This CNGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the N-terminal region of human CNGA2. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CNGA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CNGA2 |
---|---|
Synonyms | CNCA, CNCA1, CNCG2 |
Function | Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. |
Cellular Location | Membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CNGA2 represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation.
References
Qu, W., et al. J. Gen. Physiol. 127(4):375-389(2006)
Hofmann, F., et al. Pharmacol. Rev. 57(4):455-462(2005)
Yoo, D., et al. J. Biol. Chem. 279(8):6863-6873(2004)
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