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CNGA2 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CNGA2 Antibody (N-term) AP4858A
    Western blot analysis of CNGA2 Antibody (N-term) (Cat. #AP4858a) in K562 cell line lysates (35ug/lane). CNGA2 (arrow) was detected using the purified Pab.
    detail
  • FC - CNGA2 Antibody (N-term) AP4858A
    CNGA2 Antibody (N-term) (Cat. #AP4858a) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, E
Primary Accession Q16280
Other Accession Q00195, Q28718, Q62398, Q03041
Reactivity Human
Predicted Bovine, Mouse, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 76048 Da
Antigen Region 75-102 aa
Additional Information
Gene ID 1260
Other Names Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2, Cyclic nucleotide-gated channel alpha-2, CNG channel alpha-2, CNG-2, CNG2, CNGA2, CNCA, CNCA1, CNCG2
Target/Specificity This CNGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the N-terminal region of human CNGA2.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNGA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNGA2
Synonyms CNCA, CNCA1, CNCG2
Function Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)
citation

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Background

CNGA2 represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation.

References

Qu, W., et al. J. Gen. Physiol. 127(4):375-389(2006)
Hofmann, F., et al. Pharmacol. Rev. 57(4):455-462(2005)
Yoo, D., et al. J. Biol. Chem. 279(8):6863-6873(2004)

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$ 182.50
$ 70.00
Cat# AP4858A
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