ARHGAP25 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P42331 |
Other Accession | Q8BYW1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52-74 KDa |
Antigen Region | 193-219 aa |
Gene ID | 9938 |
---|---|
Other Names | Rho GTPase-activating protein 25, Rho-type GTPase-activating protein 25, ARHGAP25, KIAA0053 |
Target/Specificity | This ARHGAP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the Central region of human ARHGAP25. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ARHGAP25 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ARHGAP25 |
---|---|
Synonyms | KIAA0053 |
Function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ARHGAP25 encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration.
References
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Katoh, M., et al. Int. J. Mol. Med. 14(2):333-338(2004)
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