|Application ||WB, IHC-P, E|
|Calculated MW||52-74 KDa|
|Antigen Region||193-219 aa|
|Other Names||Rho GTPase-activating protein 25, Rho-type GTPase-activating protein 25, ARHGAP25, KIAA0053|
|Target/Specificity||This ARHGAP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the Central region of human ARHGAP25.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARHGAP25 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.|
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Provided below are standard protocols that you may find useful for product applications.
ARHGAP25 encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration.
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Marroni, F., et al. Circ Cardiovasc Genet 2(4):322-328(2009)
Katoh, M., et al. Int. J. Mol. Med. 14(2):333-338(2004)
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