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GSDMA Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GSDMA Antibody (N-term) AP4887a
    Western blot analysis of GSDMA Antibody (N-term) (Cat. #AP4887a) in mouse liver tissue lysates (35ug/lane). GSDMA (arrow) was detected using the purified Pab.
  • IHC-P - GSDMA Antibody (N-term) AP4887a
    GSDMA Antibody (N-term) (Cat. #AP4887a) IHC analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GSDMA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GSDMA Antibody (N-term) AP4887a
    GSDMA Antibody (N-term) (Cat. #AP4887a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96QA5
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49365 Da
Antigen Region 66-94 aa
Additional Information
Gene ID 284110
Other Names Gasdermin-A, Gasdermin-1, GSDMA, GSDM, GSDM1
Target/Specificity This GSDMA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human GSDMA.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGSDMA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GSDM, GSDM1
Function Induces apoptosis.
Cellular Location Cytoplasm, perinuclear region
Tissue Location Expressed predominantly in the gastrointestinal tract and in the skin at a lower level. Also detected in mammary gland. Detected in mucus-secreting pit cells of the gastric epithelium. Not expressed in gastric cancer cells
Research Areas
Citations (0)

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GSDMA induces apoptosis.


Soranzo, N., et al. Nat. Genet. 41(11):1182-1190(2009)
Saeki, N., et al. Genes Chromosomes Cancer 48(3):261-271(2009)
Tamura, M., et al. Genomics 89(5):618-629(2007)

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$ 295.00
$ 99.00
Cat# AP4887a
(40 western blots)
Availability: In Stock
Bulk Size
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