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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ERMIN Antibody (Center)   

ERMIN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ERMIN Antibody  (Center) AP4892c
    ERMIN Antibody (Center) (Cat. #AP4892c) western blot analysis in Jurkat,293 cell line lysates (35ug/lane).This demonstrates the ERMIN antibody detected the ERMIN protein (arrow).
  • FC - ERMIN Antibody  (Center) AP4892c
    ERMIN Antibody (Center) (Cat. #AP4892c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession Q8TAM6
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32783 Da
Antigen Region 113-141 aa
Additional Information
Gene ID 57471
Other Names Ermin, Juxtanodin, JN, ERMN, KIAA1189
Target/Specificity This ERMIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human ERMIN.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsERMIN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERMN
Synonyms KIAA1189
Function Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity).
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Highly expressed in adult and fetal brain. Expressed at intermediate levels in the lung and liver
Research Areas
Citations (0)

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Background

ERMIN plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. ERMIN may play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

References

Brockschnieder, D., et al. J. Neurosci. 26(3):757-762(2006)
Zhang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 102(32):11527-11532(2005)

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$ 295.00
$ 99.00
Cat# AP4892c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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