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>   home   >   Products   >   Primary Antibodies   >   HIST1H2AL Antibody (C-term)   

HIST1H2AL Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HIST1H2AL Antibody (C-term) AP4897b
    HIST1H2AL Antibody (C-term) (Cat. #AP4897b) western blot analysis in HL-60,HepG2,K562,CEM,MCF-7 cell line lysates (35ug/lane).This demonstrates the HIST1H2AL antibody detected the HIST1H2AL protein (arrow).
  • IHC-P - HIST1H2AL Antibody (C-term) AP4897b
    HIST1H2AL Antibody (C-term) (Cat. #AP4897b) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the HIST1H2AL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - HIST1H2AL Antibody (C-term) AP4897b
    HIST1H2AL Antibody (C-term) (Cat. #AP4897b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P0C0S8
Other Accession Q4FZT6, Q8BFU2, Q7L7L0, P0CC09, Q6GSS7, Q6FI13, P02262, P22752, P0C0S9, P0C170, P20671, P0C169, Q93077, P04908
Reactivity Human
Predicted Rat, Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 14091 Da
Antigen Region 103-130 aa
Additional Information
Gene ID 8329;8330;8332;8336;8969
Other Names Histone H2A type 1, H2A1, Histone H2A/p, HIST1H2AG, H2AFP
Target/Specificity This HIST1H2AL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-130 amino acids from the C-terminal region of human HIST1H2AL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIST1H2AL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms H2AFP
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Citations (0)

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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.


Lusic, M., et al. EMBO J. 22(24):6550-6561(2003)
Kzhyshkowska, J., et al. Biochem. J. 371 (PT 2), 385-393 (2003)
Marzluff, W.F., et al. Genomics 80(5):487-498(2002)

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$ 295.00
$ 99.00
Cat# AP4897b
(40 western blots)
Availability: In Stock
Bulk Size
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