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MILK2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MILK2 Antibody (C-term) AP4901b
    MILK2 Antibody (C-term) (Cat. #AP4901b) western blot analysis in HL-60,CEM cell line lysates (35ug/lane).This demonstrates the MILK2 antibody detected the MILK2 protein (arrow).
  • IHC-P - MILK2 Antibody (C-term) AP4901b
    MILK2 Antibody (C-term) (Cat. #AP4901b) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MILK2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - MILK2 Antibody (C-term) AP4901b
    MILK2 Antibody (C-term) (Cat. #AP4901b) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IY33
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 97502 Da
Antigen Region 841-870 aa
Additional Information
Gene ID 79778
Other Names MICAL-like protein 2, Junctional Rab13-binding protein, Molecule interacting with CasL-like 2, MICAL-L2, MICALL2, JRAB
Target/Specificity This MILK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 841-870 amino acids from the C-terminal region of human MILK2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMILK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms JRAB
Function Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Recycling endosome. Cell projection. Cytoplasm, cytoskeleton. Cytoplasm, cytosol
Citations (0)

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MILK2 may be a cytoskeletal regulator.


Kanda, I., et al. Oncogene 27(12):1687-1695(2008)
Terai, T., et al. Mol. Biol. Cell 17(5):2465-2475(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Terman, J.R., et al. Cell 109(7):887-900(2002)

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$ 295.00
$ 99.00
Cat# AP4901b
(40 western blots)
Availability: In Stock
Bulk Size
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