|Application ||WB, FC, E|
|Calculated MW||72513 Da|
|Antigen Region||520-547 aa|
|Other Names||Guanylate-binding protein 7, GTP-binding protein 7, GBP-7, Guanine nucleotide-binding protein 7, Guanylate-binding protein 4-like, GBP7, GBP4L|
|Target/Specificity||This GBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 520-547 amino acids from the C-terminal region of human GBP7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GBP7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Guanylate-binding proteins, such as GBP7, are induced by interferon and hydrolyze GTP to both GDP and GMP.
Olszewski, M.A., et al. J. Interferon Cytokine Res. 26(5):328-352(2006)
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