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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TNFRSF8-Y479 Antibody   

TNFRSF8-Y479 Antibody

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TNFRSF8-Y479 Antibody AP4912d
    Western blot analysis of TNFRSF8-Y479 (Cat. #AP4912d) in mouse liver tissue lysates (35ug/lane). TNFRSF8 (arrow) was detected using the purified Pab.
  • IHC-P - TNFRSF8-Y479 Antibody AP4912d
    TNFRSF8-Y479 Antibody (Cat. #AP4912d) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF8-Y479 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28908
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 63747 Da
Antigen Region 458-487 aa
Additional Information
Gene ID 943
Other Names Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Target/Specificity This TNFRSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from human TNFRSF8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNFRSF8-Y479 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD30, D1S166E
Function Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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TNFRSF8 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.


Braun, F.K., et al. J. Invest. Dermatol. 130(3):826-840(2010)
Azarpira, N., et al. Saudi J Kidney Dis Transpl 21(1):31-36(2010)
Edinger, J.T., et al. Am. J. Surg. Pathol. 33(12):1860-1868(2009)

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Cat# AP4912d
(40 western blots)
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