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PLA2G4B Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PLA2G4B Antibody (Center) AP4919c
    Western blot analysis of PLA2G4B Antibody (Center) (Cat. #AP4919c) in K562 cell line lysates (35ug/lane). PLA2G4B (arrow) was detected using the purified Pab.
    detail
  • FC - PLA2G4B Antibody (Center) AP4919c
    PLA2G4B Antibody (Center) (Cat. #AP4919c) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, E
Primary Accession P0C869
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 87978 Da
Antigen Region 396-424 aa
Additional Information
Gene ID 100137049;8681
Other Names Cytosolic phospholipase A2 beta, cPLA2-beta, Phospholipase A2 group IVB, PLA2G4B
Target/Specificity This PLA2G4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-424 amino acids from the Central region of human PLA2G4B.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPLA2G4B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G4B
Function Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling.
Cellular Location [Isoform 3]: Cytoplasm, cytosol. Mitochondrion membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein. Note=Translocates to membrane vesicles in a calcium-dependent fashion.
Tissue Location Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas
Research Areas
Citations (0)
citation

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Background

PLA2G4B transcribes naturally-occurring mRNAs that are co-transcribed products of the neighboring JMJD7 and PLA2G4B genes. Incompletely processed read-through transcripts from these two loci are abundantly expressed in most tissues, but the function of the predicted protein product has not yet been determined.

References

Ghosh, M., et al. J. Biol. Chem. 281(24):16615-16624(2006)
Tao, R., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 137B (1), 56-58 (2005)
Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005)

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$ 365.00
$ 140.00
Cat# AP4919c
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