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PSG7 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PSG7 Antibody (C-term) AP4939b
    Western blot analysis of PSG7 Antibody (C-term) (Cat. #AP4939b) in MCF-7 cell line lysates (35ug/lane). PSG7 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - PSG7 Antibody (C-term) AP4939b
    PSG7 Antibody (C-term) (Cat. #AP4939b) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PSG7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
  • FC - PSG7 Antibody (C-term) AP4939b
    PSG7 Antibody (C-term) (Cat. #AP4939b) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q13046
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47027 Da
Antigen Region 265-293 aa
Additional Information
Gene ID 5676
Other Names Putative pregnancy-specific beta-1-glycoprotein 7, PS-beta-G-7, PSBG-7, Pregnancy-specific glycoprotein 7, PSG7
Target/Specificity This PSG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-293 amino acids from the C-terminal region of human PSG7.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPSG7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSG7 (HGNC:9524)
Cellular Location Secreted.
Citations (0)
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Background

PSG7 is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene.

References

Grimwood, J., et al. Nature 428(6982):529-535(2004)
Beauchemin, N., et al. Exp. Cell Res. 252(2):243-249(1999)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)

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$ 365.00
$ 140.00
Cat# AP4939b
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