|Application ||WB, IHC-P, FC, E|
|Calculated MW||47001 Da|
|Antigen Region||265-293 aa|
|Other Names||Putative pregnancy-specific beta-1-glycoprotein 7, PS-beta-G-7, PSBG-7, Pregnancy-specific glycoprotein 7, PSG7|
|Target/Specificity||This PSG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-293 amino acids from the C-terminal region of human PSG7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PSG7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
PSG7 is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene.
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Beauchemin, N., et al. Exp. Cell Res. 252(2):243-249(1999)
Adams, M.D., et al. Nature 377 (6547 SUPPL), 3-174 (1995)
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