|Application ||WB, IHC-P, E|
|Other Accession||Q8R523, P59053|
|Calculated MW||49593 Da|
|Antigen Region||6-34 aa|
|Other Names||Potassium voltage-gated channel subfamily G member 3, Voltage-gated potassium channel subunit Kv101, Voltage-gated potassium channel subunit Kv63, KCNG3|
|Target/Specificity||This KCNG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human KCNG3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KCNG3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Potassium channel subunit. Modulates channel activity.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1|
|Tissue Location||Detected in many parts of the brain with the exception of the cerebellum, in testis, pancreas, lung, kidney, ovary, small intestine, colon, thymus, adrenal gland and spinal cord|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit functioning as a modulatory molecule.
Mederos Y Schnitzler, M., et al. J. Biol. Chem. 284(7):4695-4704(2009)
Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)
Vega-Saenz de Miera, E.C. Brain Res. Mol. Brain Res. 123 (1-2), 91-103 (2004)
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