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PTPLB Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTPLB Antibody  (C-term) AP4975b
    Western blot analysis of lysate from MCF-7 cell line, using PTPLB Antibody (C-term)(Cat. #AP4975b). AP4975b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • IHC-P - PTPLB Antibody  (C-term) AP4975b
    PTPLB Antibody (C-term) (Cat. #AP4975b) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PTPLB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PTPLB Antibody  (C-term) AP4975b
    PTPLB Antibody (C-term) (Cat. #AP4975b) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6Y1H2
Other Accession Q2KIP8, NP_940684
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28368 Da
Antigen Region 226-254 aa
Additional Information
Gene ID 201562
Other Names Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2, 3-hydroxyacyl-CoA dehydratase 2, HACD2, Protein-tyrosine phosphatase-like member B, PTPLB, HACD2
Target/Specificity This PTPLB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-254 amino acids from the C-terminal region of human PTPLB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPLB Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HACD2 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:9640}
Function Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane; Multi- pass membrane protein
Tissue Location Highly expressed in testis, spleen, prostate, colon and heart, followed by moderate expression in thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle and pancreas. Weakly detected in kidney, placenta, brain and lung.
Research Areas
Citations (0)

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PTPLB is probable anti-phosphatase.


Wang, B., et al. Mol. Cell. Biol. 24(7):2767-2778(2004)

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$ 295.00
$ 99.00
Cat# AP4975b
(40 western blots)
Availability: In Stock
Bulk Size
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