|Application ||WB, IHC-P, FC, E|
|Other Accession||Q3ZC91, NP_006705|
|Calculated MW||51260 Da|
|Antigen Region||321-349 aa|
|Other Names||Acid sphingomyelinase-like phosphodiesterase 3a, ASM-like phosphodiesterase 3a, 314-, SMPDL3A, ASML3A|
|Target/Specificity||This ASM3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-349 amino acids from the C-terminal region of human ASM3A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ASM3A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088).|
|Tissue Location||Detected in blood serum. Detected in macrophages (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Wright, K.O., et al. J. Urol. 168(6):2645-2649(2002)
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