|Application ||WB, IHC-P, FC, E|
|Other Accession||Q3ZC91, NP_006705|
|Calculated MW||51260 Da|
|Antigen Region||321-349 aa|
|Other Names||Acid sphingomyelinase-like phosphodiesterase 3a, ASM-like phosphodiesterase 3a, 314-, SMPDL3A, ASML3A|
|Target/Specificity||This ASM3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-349 amino acids from the C-terminal region of human ASM3A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ASM3A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088).|
|Tissue Location||Detected in blood serum. Detected in macrophages (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Wright, K.O., et al. J. Urol. 168(6):2645-2649(2002)
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