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EFR3A Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - EFR3A Antibody (C-term) AP4982b
    Western blot analysis of EFR3A Antibody (C-term) (Cat. #AP4982b) in K562 cell line lysates (35ug/lane). EFR3A (arrow) was detected using the purified Pab.
    detail
  • FC - EFR3A Antibody (C-term) AP4982b
    EFR3A Antibody (C-term) (Cat. #AP4982b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, E
Primary Accession Q14156
Other Accession NP_055952
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 92924 Da
Antigen Region 636-664 aa
Additional Information
Gene ID 23167
Other Names Protein EFR3 homolog A, Protein EFR3-like, EFR3A, KIAA0143
Target/Specificity This EFR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-664 amino acids from the C-terminal region of human EFR3A.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEFR3A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFR3A (HGNC:28970)
Function Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:23229899, PubMed:25608530, PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (Probable). In the complex, EFR3A probably acts as the membrane-anchoring component (PubMed:23229899). Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect (PubMed:25380825).
Cellular Location Cell membrane; Lipid-anchor. Cytoplasm, cytosol. Note=Palmitoylation anchors the protein to the plasma membrane (PubMed:23229899, PubMed:25380825, PubMed:26571211). A small amount is observed in the cytosol (PubMed:25380825).
Research Areas
Citations (0)
citation

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References

Munemoto, Y., et al. Brain Res. Mol. Brain Res. 128(2):131-140(2004)

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$ 182.50
$ 70.00
Cat# AP4982b
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