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KRT35 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q92764 |
| Other Accession | Q14532, NP_002271 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50361 Da |
| Antigen Region | 352-380 aa |
| Gene ID | 3886 |
|---|---|
| Other Names | Keratin, type I cuticular Ha5, Hair keratin, type I Ha5, Keratin-35, K35, KRT35, HHA5, HKA5, KRTHA5 |
| Target/Specificity | This KRT35 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-380 amino acids from the C-terminal region of human KRT35. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KRT35 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KRT35 |
|---|---|
| Synonyms | HHA5, HKA5, KRTHA5 |
| Tissue Location | Early expression in the hair follicle, mainly found in supramatricial cells and lowermost cortical cells of the hair bulb |
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Provided below are standard protocols that you may find useful for product applications.
Background
KRT35 is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.
References
Gilon, M., et al. Differentiation 76(5):518-530(2008)
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Cribier, B., et al. J. Invest. Dermatol. 122(5):1078-1083(2004)
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