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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mnk1 Antibody (Ab-385)   

Mnk1 Antibody (Ab-385)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mnk1 Antibody  (Ab-385) AP50021
    Western blot analysis of lysates from MCF-7,HepG2 cell line (from left to right),using Mnk1 Antibody (Ab-385)(B8376). B8376 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
  • WB - Mnk1 Antibody  (Ab-385) AP50021
    Western blot analysis of extracts from, K562 cells (Lane 1) and Jurket cells (Lane 2), using Mnk1 (Ab-385) Antibody. The lane on the left is treated with systhesized peptide.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9BUB5
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 51,47,39 KDa
Antigen Region 365-395 aa
Additional Information
Gene ID 8569
Other Names MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, Mnk1, MKNK1, MNK1
Dilution WB~~ 1:250-1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name MKNK1
Synonyms MNK1
Function May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.
Cellular Location Isoform 2: Cytoplasm.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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Background

May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7- methylguanosine-containing mRNA cap.

References

Fukunaga R.,et al.EMBO J. 16:1921-1933(1997).
Knauf U.,et al.Mol. Cell. Biol. 21:5500-5511(2001).
O'Loghlen A.,et al.Exp. Cell Res. 299:343-355(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
Cat# AP50021
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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