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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADCY9 Antibody   

ADCY9 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ADCY9 Antibody AP50059
    Western blot analysis of lysates from A549,HUVEC cell line (from left to right),using ADCY9 Antibody(C20506). C20506 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
  • IHC - ADCY9 Antibody AP50059
    Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ADCY9 antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession O60503
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 151 KDa
Antigen Region 955-983 aa
Additional Information
Gene ID 115
Other Names Adenylate cyclase type 9, ATP pyrophosphate-lyase 9, Adenylate cyclase type IX, Adenylyl cyclase 9, ADCY9, KIAA0520
Dilution WB~~ 1:1000
IHC~~1:50-1:100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name ADCY9
Synonyms KIAA0520
Function Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein- coupled receptors (PubMed:9628827, PubMed:12972952, PubMed:15879435, PubMed:10987815). Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors (PubMed:9628827).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in skeletal muscle, pancreas, lung, heart, kidney, liver, brain and placenta (PubMed:9628827, PubMed:10987815). Expressed in multiple cells of the lung, with expression highest in airway smooth muscle (PubMed:12972952)
Research Areas
Citations (0)

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Background

May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin (By similarity).

References

Hacker B.M.,et al.Genomics 50:97-104(1998).
Small K.M.,et al.Pharmacogenetics 13:535-541(2003).
Tantisira K.G.,et al.Hum. Mol. Genet. 14:1671-1677(2005).
Paterson J.M.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Toyota T.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
Cat# AP50059
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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