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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   FA13A (Cleaved-Gly39) Antibody   

FA13A (Cleaved-Gly39) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FA13A (Cleaved-Gly39) Antibody AP50064
    Western blot analysis of lysates from A431,NCI-H1299 cell line (from left to right),using FA13A (Cleaved-Gly39) Antibody(L0206). L0206 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P00488
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 83 KDa
Antigen Region 30-59 aa
Additional Information
Gene ID 2162
Other Names Coagulation factor XIII A chain, Coagulation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain, F13A1, F13A
Dilution WB~~1:500- 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name F13A1
Synonyms F13A
Function Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Cellular Location Cytoplasm. Secreted. Note=Secreted into the blood plasma Cytoplasmic in most tissues, but also secreted in the blood plasma
Research Areas
Citations (0)

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Background

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl- epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

References

Ichinose A.,et al.Biochemistry 25:6900-6906(1986).
Grundmann U.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8024-8028(1986).
Ichinose A.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:5829-5833(1988).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).

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$ 295.00
Cat# AP50064
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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