|Reactivity||Human, Mouse, Rat|
|Calculated MW||24,12,20 KDa|
|Antigen Region||129-156 aa|
|Other Names||Ras-related protein Rab-6A, Rab-6, RAB6A, RAB6|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER (PubMed:25962623).|
|Cellular Location||Golgi apparatus membrane; Lipid- anchor. Note=BICD2 facilitates its targeting to Golgi apparatus membrane Isoform 2: Golgi apparatus membrane; Lipid-anchor|
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Provided below are standard protocols that you may find useful for product applications.
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.
Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Caillol N.,et al.J. Cell. Biochem. 79:628-647(2000).
Shan J.,et al.Gene 257:67-75(2000).
Echard A.,et al.Mol. Biol. Cell 11:3819-3833(2000).
Barr F.A.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
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