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RAB6A Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RAB6A Antibody AP50071
    Western blot analysis of lysate from HT-29 cell line,using RAB6A Antibody(C18266). C18266 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P20340
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 24,12,20 KDa
Antigen Region 129-156 aa
Additional Information
Gene ID 5870
Other Names Ras-related protein Rab-6A, Rab-6, RAB6A, RAB6
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name RAB6A
Synonyms RAB6
Function Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER) (PubMed:25962623). Has a low GTPase activity (PubMed:25962623). Recruits VPS13B to the Golgi membrane (PubMed:25492866). Plays a role in neuron projection development (Probable).
Cellular Location Golgi apparatus membrane; Lipid- anchor. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P35279}; Peripheral membrane protein. Note=BICD2 facilitates its targeting to Golgi apparatus membrane. [Isoform 2]: Golgi apparatus membrane; Lipid-anchor
Tissue Location Ubiquitous..
Research Areas
Citations (0)
citation

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Background

Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.

References

Zahraoui A.,et al.J. Biol. Chem. 264:12394-12401(1989).
Caillol N.,et al.J. Cell. Biochem. 79:628-647(2000).
Shan J.,et al.Gene 257:67-75(2000).
Echard A.,et al.Mol. Biol. Cell 11:3819-3833(2000).
Barr F.A.,et al.Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.

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$ 350.00
Cat# AP50071
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Availability: 2 weeks
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