|Application ||WB, IF|
|Calculated MW||73 KDa|
|Antigen Region||592-627 aa|
|Other Names||Dual specificity protein phosphatase 16, Mitogen-activated protein kinase phosphatase 7, MAP kinase phosphatase 7, MKP-7, DUSP16, KIAA1700, MKP7|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasmic vesicle. Note=After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles|
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Provided below are standard protocols that you may find useful for product applications.
Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Masuda K.,et al.J. Biol. Chem. 276:39002-39011(2001).
Hoornaert I.,et al.Oncogene 22:7728-7736(2003).
Nagase T.,et al.DNA Res. 7:347-355(2000).
Masuda K.,et al.J. Biol. Chem. 278:32448-32456(2003).
Willoughby E.A.,et al.J. Biol. Chem. 280:25651-25658(2005).
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