|Application ||WB, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||57, KDa|
|Antigen Region||493-522 aa|
|Other Names||Thioredoxin reductase 2, mitochondrial, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3, TXNRD2, KIAA1652, TRXR2|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.|
|Tissue Location||Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low|
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Provided below are standard protocols that you may find useful for product applications.
Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.
Sun Q.-A.,et al.J. Biol. Chem. 274:24522-24530(1999).
Gasdaska P.Y.,et al.FEBS Lett. 442:105-111(1999).
Miranda-Vizuete A.,et al.Eur. J. Biochem. 261:405-412(1999).
Toji S.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Lescure A.,et al.J. Biol. Chem. 274:38147-38154(1999).
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