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TTF2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O00358 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38 KDa |
| Antigen Region | 2-32 aa |
| Gene ID | 2304 |
|---|---|
| Other Names | Forkhead box protein E1, Forkhead box protein E2, Forkhead-related protein FKHL15, HFKH4, HNF-3/fork head-like protein 5, HFKL5, Thyroid transcription factor 2, TTF-2, FOXE1, FKHL15, FOXE2, TITF2, TTF2 |
| Dilution | WB~~1:500-1:1000 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | FOXE1 |
|---|---|
| Synonyms | FKHL15, FOXE2, TITF2, TTF2 |
| Function | Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. |
| Cellular Location | Nucleus. |
| Tissue Location | Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Probable transcription factor. Could be involved in thyroid gland organogenesis.
References
Wiese S.,et al.DNA Cell Biol. 16:165-171(1997).
Chadwick B.P.,et al.Genomics 41:390-396(1997).
Macchia P.E.,et al.Biochimie 81:433-440(1999).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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