|Application ||WB, IF|
|Calculated MW||97,63,149(actual) KDa|
|Antigen Region||305-333 aa|
|Other Names||A-kinase anchor protein 1, mitochondrial, A-kinase anchor protein 149 kDa, AKAP 149, Dual specificity A-kinase-anchoring protein 1, D-AKAP-1, Protein kinase A-anchoring protein 1, PRKA1, Spermatid A-kinase anchor protein 84, S-AKAP84, AKAP1, AKAP149, PRKA1|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.|
|Cellular Location||Mitochondrion outer membrane.|
|Tissue Location||AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma|
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Provided below are standard protocols that you may find useful for product applications.
Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.
Trendelenburg G.,et al.Biochem. Biophys. Res. Commun. 225:313-319(1996).
Lin R.-Y.,et al.J. Biol. Chem. 270:27804-27811(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Hillman R.T.,et al.Genome Biol. 5:R8.1-R8.16(2004).
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