- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Calculated MW||88893 Da|
|Antigen Region||743-769 aa|
|Other Names||GDH/6PGL endoplasmic bifunctional protein, Glucose 1-dehydrogenase, Hexose-6-phosphate dehydrogenase, 6-phosphogluconolactonase, 6PGL, H6PD, GDH|
|Target/Specificity||This H6PD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 743-769 amino acids from the C-terminal region of human H6PD.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||H6PD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.|
|Cellular Location||Endoplasmic reticulum lumen. Note=Microsomes, endoplasmic reticulum lumen|
|Tissue Location||Present in most tissues examined, strongest in liver|
Provided below are standard protocols that you may find useful for product applications.
H6PD is 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.
Balazs, Z., et al. Mol. Cell. Endocrinol. 301 (1-2), 117-122 (2009) Zhang, Y.L., et al. Arch. Biochem. Biophys. 483(1):45-54(2009) Uckaya, G., et al. Diabetes Res. Clin. Pract. 82 SUPPL 2, S135-S140 (2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.