- CITATIONS: 1
|Application ||WB, IHC-P, E|
|Calculated MW||88893 Da|
|Antigen Region||743-769 aa|
|Other Names||GDH/6PGL endoplasmic bifunctional protein, Glucose 1-dehydrogenase, Hexose-6-phosphate dehydrogenase, 6-phosphogluconolactonase, 6PGL, H6PD, GDH|
|Target/Specificity||This H6PD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 743-769 amino acids from the C-terminal region of human H6PD.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||H6PD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.|
|Cellular Location||Endoplasmic reticulum lumen. Note=Microsomes, endoplasmic reticulum lumen|
|Tissue Location||Present in most tissues examined, strongest in liver|
Provided below are standard protocols that you may find useful for product applications.
H6PD is 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.
Balazs, Z., et al. Mol. Cell. Endocrinol. 301 (1-2), 117-122 (2009) Zhang, Y.L., et al. Arch. Biochem. Biophys. 483(1):45-54(2009) Uckaya, G., et al. Diabetes Res. Clin. Pract. 82 SUPPL 2, S135-S140 (2008)
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