|Application ||WB, E|
|Other Accession||Q5ZJP7, A4IFB4|
|Calculated MW||33132 Da|
|Antigen Region||95-123 aa|
|Other Names||BTB/POZ domain-containing protein KCTD7, KCTD7|
|Target/Specificity||This KCTD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the Central region of human KCTD7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KCTD7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the control of excitability of cortical neurons.|
|Cellular Location||Cell membrane. Cytoplasm, cytosol.|
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Provided below are standard protocols that you may find useful for product applications.
The KCTD gene family, including KCTD7, encode predicted proteins that contain N-terminal domain that is homologous to the T1 domain in voltage-gated potassium channels (see KCNA1; MIM 176260). KCTD7 displays a primary sequence and hydropathy profile indicating intracytoplasmic localization. EST database analysis showed that KCTD7 is expressed in human and mouse brain
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Van Bogaert, P., et al. Ann. Neurol. 61(6):579-586(2007)
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