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KRTAP1-1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KRTAP1-1 Antibody (Center) AP5050C
    Western blot analysis of KRTAP1-1 Antibody (Center) (Cat. #AP5050c) in K562 cell line lysates (35ug/lane).KRTAP1-1 (arrow) was detected using the purified Pab.
  • IHC-P - KRTAP1-1 Antibody (Center) AP5050C
    KRTAP1-1 Antibody (Center) (Cat. #AP5050c) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KRTAP1-1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - KRTAP1-1 Antibody (Center) AP5050C
    KRTAP1-1 Antibody (Center) (Cat. #AP5050c) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q07627
Other Accession Q9BYS1, Q8IUG1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18235 Da
Antigen Region 1-1 aa
Additional Information
Gene ID 81851
Other Names Keratin-associated protein 1-1, High sulfur keratin-associated protein 11, Keratin-associated protein 11, Keratin-associated protein 16, Keratin-associated protein 17, KRTAP1-1, B2A, KAP11, KAP16, KAP17, KRTAP11
Target/Specificity This KRTAP1-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human KRTAP1-1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKRTAP1-1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRTAP1-1
Synonyms B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Function In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins.
Tissue Location Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone
Research Areas
Citations (0)

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KRTAP1-1 is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21.


Shimomura, Y., et al. J. Invest. Dermatol. 118(2):226-231(2002)
Rogers, M.A., et al. J. Biol. Chem. 276(22):19440-19451(2001)

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Cat# AP5050C
(40 western blots)
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