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ARC Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | O60936 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24, 23, 29 KDa |
| Antigen Region | 175-208 aa |
| Gene ID | 8996 |
|---|---|
| Other Names | Nucleolar protein 3, Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, Nucleolar protein of 30 kDa, Nop30, NOL3, ARC, NOP |
| Dilution | WB~~ 1:1000 IHC~~1:50-1:100 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | NOL3 (HGNC:7869) |
|---|---|
| Function | [Isoform 1]: May be involved in RNA splicing. |
| Cellular Location | [Isoform 1]: Nucleus, nucleolus. Note=The SR-rich C-terminus mediates nuclear localization. [Isoform 2]: Cytoplasm. Mitochondrion {ECO:0000250|UniProtKB:Q62881}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:Q62881}. Membrane; Lipid-anchor. Note=Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress. {ECO:0000250|UniProtKB:Q62881} |
| Tissue Location | Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Isoform 1 may be involved in RNA splicing.
References
Koseki T.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:5156-5160(1998).
Stoss O.,et al.J. Biol. Chem. 274:10951-10962(1999).
Russell J.F.,et al.Ann. Neurol. 72:175-183(2012).
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