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SDCG1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SDCG1 Antibody AP50585
    Western blot analysis of lysate from HeLa cell line,using SDCG1 Antibody(AP50585). AP50585 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60524
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 123, 121, 118, 120, 31 KDa
Antigen Region 912-940 aa
Additional Information
Gene ID 9147
Other Names Nuclear export mediator factor NEMF, Antigen NY-CO-1, Serologically defined colon cancer antigen 1, NEMF, SDCCAG1
Dilution WB~~ 1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Synonyms SDCCAG1
Function Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875).
Cellular Location Nucleus.
Tissue Location Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.
Research Areas
Citations (0)

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Plays a role in nuclear export.


Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Heilig R.,et al.Nature 421:601-607(2003).
Scanlan M.J.,et al.Int. J. Cancer 76:652-658(1998).
Bi X.,et al.Oncogene 24:8229-8239(2005).

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$ 295.00
Cat# AP50585
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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