|Reactivity||Human, Mouse, Rat|
|Calculated MW||61 KDa|
|Antigen Region||282-310 aa|
|Other Names||Solute carrier family 22 member 3, Extraneuronal monoamine transporter, EMT, Organic cation transporter 3, SLC22A3, EMTH, OCT3|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen|
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Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
Gruendemann D.,et al.Nat. Neurosci. 1:349-351(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Verhaagh S.,et al.Genomics 55:209-218(1999).
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