|Application ||WB, IHC|
|Calculated MW||72 KDa|
|Antigen Region||385-414 aa|
|Other Names||Sodium/nucleoside cotransporter 2, Concentrative nucleoside transporter 2, CNT 2, hCNT2, Na(+)/nucleoside cotransporter 2, Sodium-coupled nucleoside transporter 2, Sodium/purine nucleoside co-transporter, SPNT, Solute carrier family 28 member 2, SLC28A2, CNT2|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung|
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Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.
Wang J.,et al.Am. J. Physiol. 273:F1058-F1065(1997).
Ritzel M.W.L.,et al.Mol. Membr. Biol. 15:203-211(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Loewen S.K.,et al.J. Biol. Chem. 274:24475-24484(1999).
Owen R.P.,et al.Pharmacogenet. Genomics 15:83-90(2005).
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