|Application ||WB, IF|
|Calculated MW||41 KDa|
|Antigen Region||165-192 aa|
|Other Names||Cytosolic 5'-nucleotidase 1A, cN1A, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.|
|Tissue Location||Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas|
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Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.
Hunsucker S.A.,et al.J. Biol. Chem. 276:10498-10504(2001).
Lowenstein J.M.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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