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CLCC1 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q96S66 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 62,56,47,40 KDa |
| Antigen Region | 410-436 aa |
| Gene ID | 23155 |
|---|---|
| Other Names | Chloride channel CLIC-like protein 1, Mid-1-related chloride channel protein 1, CLCC1, KIAA0761, MCLC |
| Dilution | WB~~ 1:500 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | CLCC1 |
|---|---|
| Synonyms | KIAA0761, MCLC |
| Function | Seems to act as a chloride ion channel (PubMed:30157172). Plays a role in retina development (PubMed:30157172). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9WU61}; Multi-pass membrane protein. Nucleus membrane {ECO:0000250|UniProtKB:Q9WU61}; Multi- pass membrane protein. Note=Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes |
| Tissue Location | Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Seems to act as a chloride ion channel (By similarity).
References
Nagasawa M.,et al.J. Biol. Chem. 276:20413-20418(2001).
Nagase T.,et al.DNA Res. 5:277-286(1998).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
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