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GBA3 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GBA3 Antibody AP50623
    Western blot analysis of lysates from human liver and spleen tissue lysate(from left to right),using GBA3 Antibody(AP50623). AP50623 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9H227
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 54,18 KDa
Antigen Region 302-331 aa
Additional Information
Gene ID 57733
Other Names Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, CBG, CBGL1
Dilution WB~~ 1:500-1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name GBA3
Synonyms CBG, CBGL1
Function Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.
Cellular Location Cytoplasm, cytosol
Tissue Location Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney Down-regulated in renal cell carcinomas and hepatocellular carcinomas.
Research Areas
Citations (0)

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Background

Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta- glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.

References

Yahata K.,et al.J. Mol. Med. 78:389-394(2000).
de Graaf M.,et al.Biochem. J. 356:907-910(2001).
Berrin J.-G.,et al.Eur. J. Biochem. 269:249-258(2002).
Hays W.S.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
Cat# AP50623
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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