|Calculated MW||27 KDa|
|Antigen Region||41-69 aa|
|Other Names||Chloride intracellular channel protein 3, CLIC3|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Can insert into membranes and form chloride ion channels. May participate in cellular growth control.|
|Cellular Location||Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Note=Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).|
|Tissue Location||Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.|
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Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Qian Z.,et al.J. Biol. Chem. 274:1621-1627(1999).
Money T.T.,et al.Placenta 28:429-436(2007).
Littler D.R.,et al.Proteins 78:1594-1600(2010).
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