|Calculated MW||27 KDa|
|Antigen Region||41-69 aa|
|Other Names||Chloride intracellular channel protein 3, CLIC3|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Can insert into membranes and form chloride ion channels. May participate in cellular growth control.|
|Cellular Location||Nucleus. Membrane; Single-pass membrane protein. Cytoplasm. Note=Predominantly nuclear. Some protein was found in the cytoplasm. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).|
|Tissue Location||Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Qian Z.,et al.J. Biol. Chem. 274:1621-1627(1999).
Money T.T.,et al.Placenta 28:429-436(2007).
Littler D.R.,et al.Proteins 78:1594-1600(2010).
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