|Application ||WB, IHC|
|Calculated MW||45 KDa|
|Antigen Region||220-248 aa|
|Other Names||Renin, Angiotensinogenase, REN|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.|
|Cellular Location||Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2|
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Provided below are standard protocols that you may find useful for product applications.
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Imai T.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:7405-7409(1983).
Morris B.J.,et al.Clin. Sci. 71:345-355(1986).
Hardman J.A.,et al.DNA 3:457-468(1984).
Rieder M.J.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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