REN Antibody
Affinity-Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
---|---|
Primary Accession | P00797 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 45 KDa |
Antigen Region | 220-248 aa |
Gene ID | 5972 |
---|---|
Other Names | Renin, Angiotensinogenase, REN |
Dilution | WB~~1:1000 IHC~~1:50-1:100 |
Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol. |
Storage Conditions | -20℃ |
Name | REN |
---|---|
Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
Cellular Location | Secreted. Membrane. Note=Associated to membranes via binding to ATP6AP2. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
References
Imai T.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:7405-7409(1983).
Morris B.J.,et al.Clin. Sci. 71:345-355(1986).
Hardman J.A.,et al.DNA 3:457-468(1984).
Rieder M.J.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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