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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TIMP2 Antibody   

TIMP2 Antibody

Affinity-Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TIMP2 Antibody AP50675
    Western blot analysis of lysate from HT1080 cell line,using TIMP2 Antibody(AP50675). AP50675 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • IF - TIMP2 Antibody AP50675
    Immunofluorescence analysis of A549 cells, using TIMP2 antibody (#AP50675).
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession P16035
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 24 KDa
Antigen Region 40-68 aa
Additional Information
Gene ID 7077
Other Names Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2
Dilution WB~~1:1000
IF~~1:100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name TIMP2
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

References

Stetler-Stevenson W.G.,et al.J. Biol. Chem. 265:13933-13938(1990).
Boone T.C.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2800-2804(1990).
Hammani K.,et al.J. Biol. Chem. 271:25498-25505(1996).
Malik K.,et al.Submitted (AUG-1990) to the EMBL/GenBank/DDBJ databases.
Stetler-Stevenson W.G.,et al.J. Biol. Chem. 264:17374-17378(1989).

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$ 295.00
Cat# AP50675
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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